Courses:

Tumor Pathophysiology and Transport Phenomena >> Content Detail



Syllabus



Syllabus



Description


Tumor pathophysiology plays a central role in the growth, invasion, metastasis and treatment of solid tumors. This class applies principles of transport phenomena to develop a systems-level, quantitative understanding of angiogenesis, blood flow and microcirculation, metabolism and microenvironment, transport and binding of small and large molecules, movement of cancer and immune cells, metastatic process, and treatment response.



Requirements


There are no exams in this class, but there is a substantial term paper. Each student must prepare an in-class presentation on his or her paper, and the last two days of class are devoted to these presentations.



Calendar



LEC #TOPICSLECTURERS
1Delivery of Molecular Medicine to Tumors I: Vascular Transport and the Normalization HypothesisR. K. Jain (HMS/MGH)
2Delivery of Molecular Medicine to Tumors II: Interstitial and Lymphatic TransportR. K. Jain (HMS/MGH)
3Controlled Release of Drugs to TumorsR. Langer (MIT)
4Role of Bone Marrow-Derived Cells in CancerD. Duda (HMS)
5Rules for Making Human TumorsR. Weinberg (MIT)
6Angiogenesis and Anti-angiogenesisP. D'Amore (HMS/SERI)
7MetastasisM. Moses (HMS/CH)
8Extracellular MatrixR. Kalluri (HMS/BIDMC)
9Mathematical Modeling of Drug Delivery and MetastasisL. Munn (HMS/MGH)
10-11Class Presentations

 








© 2010-2021 OpenCollege.com, All Rights Reserved.
Open College is a service mark of AmeriCareers LLC.