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Calendar

LEC #TOPICSKEY DATES
Part I: Systems Microbiology - 'The Cell as a Well-stirred Bioreactor'
1Introduction

Michaelis-Menten Kinetics
2Equilibrium Binding

Cooperativity
3Lambda Phage

Multistability
4Multistability (cont.)
5Synthetic Genetic Switches
6Stability Analysis
7Introduction E. coli Chemotaxis
8Fine-tuned versus Robust Chemotaxis ModelsProblem set 1 due
9Wrapping up Chemotaxis
10Genetic Oscillators
11Genetic Oscillators (cont.)
12Stochastic Chemical KineticsProblem set 2 due
13Stochastic Chemical Kinetics (cont.)
Part II: Cell Systems Biology - 'The Importance of Diffusion and Gradients for Cellular Regulation'
14Introduction Cell Systems Biology

Fick's Laws
15Local Excitation

Global Inhibition Theory
16Local Excitation (cont.)

Global Inhibition Theory (cont.)
Problem set 3 due
17Rapid Pole-to-pole Oscillations in E. coli
18Rapid Pole-to-pole Oscillations in E. coli (cont.)
19Models for Eukaryotic Gradient SensingProblem set 4 due
20Models for Eukaryotic Gradient Sensing (cont.)
21Modeling Cytoskeleton Dynamics
22Modeling Cytoskeleton Dynamics (cont.)Problem set 5 due
Part III: Developmental Systems Biology - 'Building an Organism Starting From a Single Cell'
23Quorum Sensing
24Final Problem Set Question Hour
25Drosophila DevelopmentTake home final due

 








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