1 | Introduction (PDF) |
2 | Discovery of the Ubiquitin Conjugation System (PDF) |
3 | Protein Degradation in Trafficking Membranes I: Endoplasmic Reticulum Associated Degradation (ERAD) Pathway (PDF) |
4 | Protein Degradation in Trafficking Membranes II: Endocytosis and lysosomal Degradation (PDF) |
5 | Role of Ubiquitination in Transcriptional Regulation (PDF) |
6 | Role of Ubiquitination in Cell Cycle Control and Programmed Cell Death (PDF) |
7 | Ubiquitin-like Proteins (PDF) |
8 | Functions of the Ubiquitin-Proteasome System in the Immune System (PDF) |
9 | Ubiquitin and Cancer (PDF) |
10 | Ubiquitin and Neurodegenerative Diseases: Alzheimer's and Parkinson's Diseases (PDF) |
11 | More Diseases Involving Ubiquitin: Huntington's and Von Hippel-Lindau Disease (PDF) |
12 | Too Much Degradation Can Be as Bad as Not Enough: Cystic Fibrosis and Liddle's Syndrome (PDF) |
13 | Potential Therapeutic Strategies in Ubiquitin-Related Diseases (PDF) |
14 | Oral Presentations
Final Comments and Course Evaluation |